Allelic loss on chromosome band 18p11.3 occurs early and reveals heterogeneity in breast cancer progression

We examined the stage specificity and heterogeneity of 18p11 alterations in a series of tumors representing 96 microdissected samples. Significant loss of heterozygosity (LOH) (63%) was found, with 56% occurring early in ductal carcinoma in situ. Although most cases indicated LOH was clonally inheri...

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Publié dans:	Breast Cancer Res
Auteurs principaux:	Kittiniyom, Kanokwan, Gorse, Karen M, Dalbegue, Fabienne, Lichy, Jack H, Taubenberger, Jeffery K, Newsham, Irene F
Format:	Artigo
Langue:	Inglês
Publié:	BMC 2001
Sujets:	Primary Research
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC30703/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11305954/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/bcr294
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