Allelic loss on chromosome band 18p11.3 occurs early and reveals heterogeneity in breast cancer progression
We examined the stage specificity and heterogeneity of 18p11 alterations in a series of tumors representing 96 microdissected samples. Significant loss of heterozygosity (LOH) (63%) was found, with 56% occurring early in ductal carcinoma in situ. Although most cases indicated LOH was clonally inheri...
Αποθηκεύτηκε σε:
| Εκδόθηκε σε: | Breast Cancer Res |
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| Κύριοι συγγραφείς: | , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
BMC
2001
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC30703/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11305954/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/bcr294 |
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