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Progressive NKCC1-Dependent Neuronal Chloride Accumulation during Neonatal Seizures
Seizures induce excitatory shifts in the reversal potential for GABA(A)-receptor-mediated responses, which may contribute to the intractability of electro-encephalographic seizures and preclude the efficacy of widely used GABAergic anticonvulsants such as phenobarbital. We now report that, in intact...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3070296/ https://ncbi.nlm.nih.gov/pubmed/20810895 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1769-10.2010 |
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