Local Impermeant Anions Establish the Neuronal Chloride Concentration

Neuronal chloride concentration [Cl(−)](i) is an important determinant of GABA(A) receptor (GABA(A)R)-mediated inhibition and cytoplasmic volume regulation. Equilibrative cation-chloride cotransporters (CCC) move Cl(−) across the membrane, but accumulating evidence suggests factors other than the bu...

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Publicado en:Science
Autores principales: Glykys, J, Dzhala, V, Egawa, K, Balena, T, Saponjian, Y, Kuchibhotla, KV, Bacskai, BJ, Kahle, KT, Zeuthen, T, Staley, KJ
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4220679/
https://ncbi.nlm.nih.gov/pubmed/24503855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1245423
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