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Chloride dysregulation, seizures, and cerebral edema: a relationship with therapeutic potential

Pharmaco-resistant seizures and cytotoxic cerebral edema are serious complications of ischemic and traumatic brain injury. Intraneuronal Cl(−) concentration ([Cl(−)](i)) regulation impacts both cell volume homeostasis and Cl(−) permeable GABA(A) receptor-dependent membrane excitability. Understandin...

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Foilsithe in:Trends Neurosci
Main Authors: Glykys, J., Dzhala, V., Egawa, K., Kahle, K.T., Delpire, E., Staley, K.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5473173/
https://ncbi.nlm.nih.gov/pubmed/28431741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tins.2017.03.006
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