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Presence of negative torsional tension in the promoter region of the transcriptionally poised dihydrofolate reductase gene in vivo.
DNA topology has been suggested to play an important role in the process of transcription. Negative torsional tension has been shown to stimulate both pre-initiation complex formation and promoter clearance on plasmid DNA in vitro. We recently showed that genomic DNA in human cells contains localize...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1995
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC306936/ https://ncbi.nlm.nih.gov/pubmed/7784183 |
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