HhaI and HpaII DNA methyltransferases bind DNA mismatches, methylate uracil and block DNA repair.

The hydrolytic deamination of 5-methylcytosine (5-mC) to thymine (T) is believed to be responsible for the high mutability of the CpG dinucleotide in DNA. We have shown a possible alternate mechanism for mutagenesis at CpG in which HpaII DNA-(cytosine-5) methyltransferase (M.HpaII) can enzymatically...

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書目詳細資料

發表在:	Nucleic Acids Res
Principais autores:	Yang, A S, Shen, J C, Zingg, J M, Mi, S, Jones, P A
格式:	Artigo
語言:	Inglês
出版:	Oxford University Press 1995
在線閱讀:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC306865/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7753629/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/23.8.1380
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