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Binding of ATP to the CBS domains in the C-terminal region of CLC-1
The common gating of CLC-1 has been shown to be inhibited by intracellular adenosine triphosphate (ATP) in acidic pH conditions. Such modulation is thought to be mediated by direct binding of ATP to the cystathionine β-synthase (CBS) domains at the C-terminal cytoplasmic region of CLC-1. Guided by t...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Rockefeller University Press
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3068280/ https://ncbi.nlm.nih.gov/pubmed/21444658 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201010495 |
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