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Influences of Mutations on the Electrostatic Binding Free Energies of Chloride Ions in Escherichia Coli ClC

Mutations in ClC channel proteins may cause serious functional changes and even diseases. The function of ClC proteins mainly manifests as Cl(−) transport, which is related to the binding free energies of chloride ions. Therefore, the influence of a mutation on ClC function can be studied by investi...

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Detalhes bibliográficos
Main Authors: Yu, Tao, Wang, Xiao-Qing, Sang, Jian-Ping, Pan, Chun-Xu, Zou, Xian-Wu, Chen, Tsung-Yu, Zou, Xiaoqin
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3411325/
https://ncbi.nlm.nih.gov/pubmed/22612693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp300430f
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