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Extracellular Zinc Ion Inhibits ClC-0 Chloride Channels by Facilitating Slow Gating

Extracellular Zn(2+) was found to reversibly inhibit the ClC-0 Cl(−) channel. The apparent on and off rates of the inhibition were highly temperature sensitive, suggesting an effect of Zn(2+) on the slow gating (or inactivation) of ClC-0. In the absence of Zn(2+), the rate of the slow-gating relaxat...

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書目詳細資料
主要作者: Chen, Tsung-Yu
格式: Artigo
語言:Inglês
出版: The Rockefeller University Press 1998
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2229451/
https://ncbi.nlm.nih.gov/pubmed/9834141
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