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Influences of Mutations on the Electrostatic Binding Free Energies of Chloride Ions in Escherichia Coli ClC

Mutations in ClC channel proteins may cause serious functional changes and even diseases. The function of ClC proteins mainly manifests as Cl(−) transport, which is related to the binding free energies of chloride ions. Therefore, the influence of a mutation on ClC function can be studied by investi...

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Hlavní autoři: Yu, Tao, Wang, Xiao-Qing, Sang, Jian-Ping, Pan, Chun-Xu, Zou, Xian-Wu, Chen, Tsung-Yu, Zou, Xiaoqin
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3411325/
https://ncbi.nlm.nih.gov/pubmed/22612693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp300430f
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