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Binding of ATP to the CBS domains in the C-terminal region of CLC-1

The common gating of CLC-1 has been shown to be inhibited by intracellular adenosine triphosphate (ATP) in acidic pH conditions. Such modulation is thought to be mediated by direct binding of ATP to the cystathionine β-synthase (CBS) domains at the C-terminal cytoplasmic region of CLC-1. Guided by t...

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Detalhes bibliográficos
Main Authors: Tseng, Pang-Yen, Yu, Wei-Ping, Liu, Hao-Yang, Zhang, Xiao-Dong, Zou, Xiaoqin, Chen, Tsung-Yu
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3068280/
https://ncbi.nlm.nih.gov/pubmed/21444658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201010495
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