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Sequence context of antisense RelA/NF-kappa B phosphorothioates determines specificity.
The use of antisense oligomers to achieve inhibition of gene expression is complicated by frequent non-specific effects, and even the control oligomers often exhibit sequence-specific effects. We have recently shown that in diverse tumor-derived cell lines, a 24mer phosphorothioate oligomer antisens...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
1995
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC306823/ https://ncbi.nlm.nih.gov/pubmed/7739892 |
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