Sequence context of antisense RelA/NF-kappa B phosphorothioates determines specificity.
The use of antisense oligomers to achieve inhibition of gene expression is complicated by frequent non-specific effects, and even the control oligomers often exhibit sequence-specific effects. We have recently shown that in diverse tumor-derived cell lines, a 24mer phosphorothioate oligomer antisens...
Guardat en:
| Publicat a: | Nucleic Acids Res |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
1995
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| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC306823/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7739892/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/23.7.1146 |
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