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A modified single-strand annealing model best explains the joining of DNA double-strand breaks mammalian cells and cell extracts.

The joining of DNA double-strand breaks in vivo is frequently accompanied by the loss of a few nucleotides at the junction between the interacting partners. In vitro systems mimic this loss and, on detailed analysis, have suggested two models for the mechanism of end-joining. One invokes the use of...

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Hlavní autoři: Nicolás, A L, Munz, P L, Young, C S
Médium: Artigo
Jazyk:Inglês
Vydáno: 1995
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC306802/
https://ncbi.nlm.nih.gov/pubmed/7731791
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