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Late induction of human DNA ligase I after UV-C irradiation.

We have studied the regulation of DNA ligase I gene expression in UV-C irradiated human primary fibroblasts. An increase of approximately 6-fold both in DNA ligase I messenger and activity levels was observed 24 h after UV treatment, when nucleotide excision repair (NER) is no longer operating. DNA...

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Autors principals: Montecucco, A, Savini, E, Biamonti, G, Stefanini, M, Focher, F, Ciarrocchi, G
Format: Artigo
Idioma:Inglês
Publicat: 1995
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC306792/
https://ncbi.nlm.nih.gov/pubmed/7731810
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