Requirement for the Amino-Terminal Domain of Sindbis Virus nsP4 during Virus Infection

The Sindbis virus RNA-dependent RNA polymerase nsP4 possesses an amino-terminal region that is unique to alphaviruses and is predicted to be disordered. To determine the importance of this region during alphavirus replication, 29 mutations were introduced, and resultant viruses were assessed for gro...

Full description

Saved in:
Bibliographic Details
Main Authors: Rupp, Jonathan C., Jundt, Natasha, Hardy, Richard W.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2011
Subjects:
Genome Replication and Regulation of Viral Gene Expression
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067876/
https://ncbi.nlm.nih.gov/pubmed/21248049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02058-10
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items