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Requirement for the Amino-Terminal Domain of Sindbis Virus nsP4 during Virus Infection

The Sindbis virus RNA-dependent RNA polymerase nsP4 possesses an amino-terminal region that is unique to alphaviruses and is predicted to be disordered. To determine the importance of this region during alphavirus replication, 29 mutations were introduced, and resultant viruses were assessed for gro...

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書目詳細資料
Main Authors: Rupp, Jonathan C., Jundt, Natasha, Hardy, Richard W.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology (ASM) 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067876/
https://ncbi.nlm.nih.gov/pubmed/21248049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02058-10
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