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In Vitro Synthesis of Sindbis Virus Genomic and Subgenomic RNAs: Influence of nsP4 Mutations and Nucleoside Triphosphate Concentrations

Two positive-strand mRNAs are made in Sindbis virus-infected cells, the genomic (G) RNA and the subgenomic (SG) RNA. In mosquito cells infected with wild-type (wt) Sindbis virus, the latter is made in excess over the former; however, in cells infected with SVpzf or SVcpc more G RNA is made than SG R...

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Detalhes bibliográficos
Main Authors: Li, Mei-Ling, Wang, Hongtao, Stollar, Victor
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826077/
https://ncbi.nlm.nih.gov/pubmed/20053747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01561-09
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