Parity and Placental Infection Affect Antibody Responses against Plasmodium falciparum during Pregnancy

Women are at higher risk of Plasmodium falciparum infection when pregnant. The decreasing risk of malaria with subsequent pregnancies is attributed to parity-dependent acquisition of antibodies against placental parasites expressing variant surface antigens, VAR2CSA, that mediate placental sequestra...

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Hlavní autoři: Mayor, Alfredo, Rovira-Vallbona, Eduard, Machevo, Sonia, Bassat, Quique, Aguilar, Ruth, Quintó, Llorenç, Jiménez, Alfons, Sigauque, Betuel, Dobaño, Carlota, Kumar, Sanjeev, Singh, Bijender, Gupta, Puneet, Chauhan, Virander S., Chitnis, Chetan E., Alonso, Pedro L., Menéndez, Clara
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2011
Témata:
Microbial Immunity and Vaccines
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067565/
https://ncbi.nlm.nih.gov/pubmed/21300778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01000-10
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