Parity and Placental Infection Affect Antibody Responses against Plasmodium falciparum during Pregnancy

Women are at higher risk of Plasmodium falciparum infection when pregnant. The decreasing risk of malaria with subsequent pregnancies is attributed to parity-dependent acquisition of antibodies against placental parasites expressing variant surface antigens, VAR2CSA, that mediate placental sequestra...

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Detalhes bibliográficos
Main Authors: Mayor, Alfredo, Rovira-Vallbona, Eduard, Machevo, Sonia, Bassat, Quique, Aguilar, Ruth, Quintó, Llorenç, Jiménez, Alfons, Sigauque, Betuel, Dobaño, Carlota, Kumar, Sanjeev, Singh, Bijender, Gupta, Puneet, Chauhan, Virander S., Chitnis, Chetan E., Alonso, Pedro L., Menéndez, Clara
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2011
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067565/
https://ncbi.nlm.nih.gov/pubmed/21300778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01000-10
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