Parity and Placental Infection Affect Antibody Responses against Plasmodium falciparum during Pregnancy

Women are at higher risk of Plasmodium falciparum infection when pregnant. The decreasing risk of malaria with subsequent pregnancies is attributed to parity-dependent acquisition of antibodies against placental parasites expressing variant surface antigens, VAR2CSA, that mediate placental sequestra...

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Bibliografische gegevens
Hoofdauteurs: Mayor, Alfredo, Rovira-Vallbona, Eduard, Machevo, Sonia, Bassat, Quique, Aguilar, Ruth, Quintó, Llorenç, Jiménez, Alfons, Sigauque, Betuel, Dobaño, Carlota, Kumar, Sanjeev, Singh, Bijender, Gupta, Puneet, Chauhan, Virander S., Chitnis, Chetan E., Alonso, Pedro L., Menéndez, Clara
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology (ASM) 2011
Onderwerpen:
Microbial Immunity and Vaccines
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067565/
https://ncbi.nlm.nih.gov/pubmed/21300778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01000-10
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