Parity and Placental Infection Affect Antibody Responses against Plasmodium falciparum during Pregnancy

Women are at higher risk of Plasmodium falciparum infection when pregnant. The decreasing risk of malaria with subsequent pregnancies is attributed to parity-dependent acquisition of antibodies against placental parasites expressing variant surface antigens, VAR2CSA, that mediate placental sequestra...

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Detalles Bibliográficos
Autores principales: Mayor, Alfredo, Rovira-Vallbona, Eduard, Machevo, Sonia, Bassat, Quique, Aguilar, Ruth, Quintó, Llorenç, Jiménez, Alfons, Sigauque, Betuel, Dobaño, Carlota, Kumar, Sanjeev, Singh, Bijender, Gupta, Puneet, Chauhan, Virander S., Chitnis, Chetan E., Alonso, Pedro L., Menéndez, Clara
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2011
Materias:
Microbial Immunity and Vaccines
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067565/
https://ncbi.nlm.nih.gov/pubmed/21300778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01000-10
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