Stabilization of double-stranded oligonucleotides using backbone-linked disulfide bridges.

A convenient, practical route to the synthesis of disulfide-bridged oligonucleotides has been developed. Aliphatic linkers with terminal thiol groups have been attached to the phosphodiester backbones of partially or fully complementary oligonucleotide sequences and oxidized to yield covalently clos...

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Bibliográfalaš dieđut

Publikašuvnnas:	Nucleic Acids Res
Váldodahkkit:	Gao, H, Yang, M, Cook, A F
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	Oxford University Press 1995
Fáttát:	Research Article
Liŋkkat:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC306667/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7862534/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/23.2.285
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