RNAi-Based Screening Identifies Kinases Interfering with Dioxin-Mediated Up-Regulation of CYP1A1 Activity

BACKGROUND: The aryl hydrocarbon receptor (AhR) is a transcription factor activated by several environmental pollutants, such as 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), and involved in carcinogenesis and various physiological processes, including immune response and endocrine functions. Characte...

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Bibliografiske detaljer
Main Authors: Gilot, David, Le Meur, Nolwenn, Giudicelli, Fanny, Le Vée, Marc, Lagadic-Gossmann, Dominique, Théret, Nathalie, Fardel, Olivier
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3066211/
https://ncbi.nlm.nih.gov/pubmed/21479225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018261
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