Benzo(a)pyrene triggers desensitization of β2-adrenergic pathway

Exposure to environmental polycyclic aromatic hydrocarbons (PAHs), such as benzo(a)pyrene (B(a)P), has been linked to several health-threatening risks. PAHs were also shown to hinder adrenergic receptor (ADR) responses. As we previously demonstrated that B(a)P can directly interact with the β2ADR, w...

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Udgivet i:Sci Rep
Main Authors: Mayati, Abdullah, Podechard, Normand, Rineau, Manuelle, Sparfel, Lydie, Lagadic-Gossmann, Dominique, Fardel, Olivier, Le Ferrec, Eric
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5468268/
https://ncbi.nlm.nih.gov/pubmed/28607424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03646-4
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