Opposing Roles for Membrane Bound and Soluble Fas Ligand in Glaucoma-Associated Retinal Ganglion Cell Death

Glaucoma, the most frequent optic neuropathy, is a leading cause of blindness worldwide. Death of retinal ganglion cells (RGCs) occurs in all forms of glaucoma and accounts for the loss of vision, however the molecular mechanisms that cause RGC loss remain unclear. The pro-apoptotic molecule, Fas li...

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Detalhes bibliográficos
Main Authors: Gregory, Meredith S., Hackett, Caroline G., Abernathy, Emma F., Lee, Karen S., Saff, Rebecca R., Hohlbaum, Andreas M., Moody, Krishna-sulayman L., Hobson, Maura W., Jones, Alexander, Kolovou, Paraskevi, Karray, Saoussen, Giani, Andrea, John, Simon W. M., Chen, Dong Feng, Marshak-Rothstein, Ann, Ksander, Bruce R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3066205/
https://ncbi.nlm.nih.gov/pubmed/21479271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017659
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