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Dynamic Kinetic Resolution of Biaryl Atropisomers via Peptide-Catalyzed Asymmetric Bromination
Despite the widespread use of axially chiral, or atropisomeric, biaryl ligands in modern synthesis, and the occurrence of numerous natural products exhibiting axial chirality, general catalytic methods for the direct asymmetric preparation of this compound class have proven elusive. Here we present...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3066098/ https://ncbi.nlm.nih.gov/pubmed/20522769 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1188403 |
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