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Dynamic Kinetic Resolution of Biaryl Atropisomers via Peptide-Catalyzed Asymmetric Bromination

Despite the widespread use of axially chiral, or atropisomeric, biaryl ligands in modern synthesis, and the occurrence of numerous natural products exhibiting axial chirality, general catalytic methods for the direct asymmetric preparation of this compound class have proven elusive. Here we present...

詳細記述

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書誌詳細
主要な著者: Gustafson, Jeffrey L., Lim, Daniel, Miller, Scott J.
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3066098/
https://ncbi.nlm.nih.gov/pubmed/20522769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1188403
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