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Crystal structures of the metal-dependent 2-dehydro-3-deoxy-galactarate aldolase suggest a novel reaction mechanism

Carbon–carbon bond formation is an essential reaction in organic chemistry and the use of aldolase enzymes for the stereochemical control of such reactions is an attractive alternative to conventional chemical methods. Here we describe the crystal structures of a novel class II enzyme, 2-dehydro-3-d...

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Bibliografiske detaljer
Main Authors: Izard, Tina, Blackwell, Nicholas C.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC306599/
https://ncbi.nlm.nih.gov/pubmed/10921867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.15.3849
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