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Purification, crystallization and preliminary crystallographic studies on 2-dehydro-3-deoxygalactarate aldolase from Leptospira interrogans

2-Dehydro-3-deoxygalactarate (DDG) aldolase is a member of the class II aldolase family and plays an important role in the pyruvate-metabolism pathway, catalyzing the reversible aldol cleavage of DDG to pyruvate and tartronic semialdehyde. As it is a potential novel antibiotic target, it is necessar...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Li, Xu, Huang, Hua, Song, Xiaomin, Wang, Yanli, Xu, Hang, Teng, Maikun, Gong, Weimin
Format: Artigo
Sprache:Inglês
Veröffentlicht: International Union of Crystallography 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2225365/
https://ncbi.nlm.nih.gov/pubmed/17142914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S174430910604797X
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