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Crystal structures of the metal-dependent 2-dehydro-3-deoxy-galactarate aldolase suggest a novel reaction mechanism

Carbon–carbon bond formation is an essential reaction in organic chemistry and the use of aldolase enzymes for the stereochemical control of such reactions is an attractive alternative to conventional chemical methods. Here we describe the crystal structures of a novel class II enzyme, 2-dehydro-3-d...

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Détails bibliographiques
Auteurs principaux: Izard, Tina, Blackwell, Nicholas C.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2000
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC306599/
https://ncbi.nlm.nih.gov/pubmed/10921867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.15.3849
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