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Crystal structures of the metal-dependent 2-dehydro-3-deoxy-galactarate aldolase suggest a novel reaction mechanism

Carbon–carbon bond formation is an essential reaction in organic chemistry and the use of aldolase enzymes for the stereochemical control of such reactions is an attractive alternative to conventional chemical methods. Here we describe the crystal structures of a novel class II enzyme, 2-dehydro-3-d...

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Hlavní autoři: Izard, Tina, Blackwell, Nicholas C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2000
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC306599/
https://ncbi.nlm.nih.gov/pubmed/10921867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.15.3849
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