Lanean...

Drug export and allosteric coupling in a multidrug transporter revealed by molecular simulations

Multidrug resistance is a serious problem in current chemotherapy. The efflux system largely responsible for resistance in Escherichia coli contains the drug transporter, AcrB. The structures of AcrB were solved in 2002 as the symmetric homo-trimer, and then in 2006 as the asymmetric homo-trimer. Th...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Yao, Xin-Qiu, Kenzaki, Hiroo, Murakami, Satoshi, Takada, Shoji
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3065909/
https://ncbi.nlm.nih.gov/pubmed/21081915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1116
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!