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Detection and identification of 4-hydroxy-2-nonenal Schiff-base adducts along with products of Michael addition using data-dependent neutral loss-driven MS(3) acquisition: method evaluation through an in vitro study on cytochrome c oxidase modifications
We report a data-dependent neutral-loss driven MS(3) acquisition to enhance, in addition to abundant Michael adducts, the detection and localization of Schiff-base adducts of proteins and 4-hydroxy-2-nonenal, a reactive end-products of lipid peroxidation. In vitro modification of cytochrome c oxidas...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3065305/ https://ncbi.nlm.nih.gov/pubmed/19771555 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.200900116 |
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