Targeted inhibition of calcineurin attenuates cardiac hypertrophy in vivo
The Ca(2+)-calmodulin-activated Ser/Thr protein phosphatase calcineurin and the downstream transcriptional effectors of calcineurin, nuclear factor of activated T cells, have been implicated in the hypertrophic response of the myocardium. Recently, the calcineurin inhibitory agents cyclosporine A an...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC30652/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11248077/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.031371998 |
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