Targeted inhibition of calcineurin attenuates cardiac hypertrophy in vivo

The Ca(2+)-calmodulin-activated Ser/Thr protein phosphatase calcineurin and the downstream transcriptional effectors of calcineurin, nuclear factor of activated T cells, have been implicated in the hypertrophic response of the myocardium. Recently, the calcineurin inhibitory agents cyclosporine A an...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: De Windt, Leon J., Lim, Hae W., Bueno, Orlando F., Liang, Qiangrong, Delling, Ulrike, Braz, Julian C., Glascock, Betty J., Kimball, Thomas F., del Monte, Federica, Hajjar, Roger J., Molkentin, Jeffery D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The National Academy of Sciences 2001
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC30652/
https://ncbi.nlm.nih.gov/pubmed/11248077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.031371998
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