The RNA Exosome Targets the AID Cytidine Deaminase to Both Strands of Transcribed Duplex DNA Substrates

Activation Induced cytidine Deaminase (AID) initiates Immunoglobulin (Ig) heavy chain (IgH) class switch recombination (CSR) and Ig variable region somatic hypermutation (SHM) in B lymphocytes by deaminating cytidines on template and non-template strands of transcribed DNA substrates. However, the m...

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Main Authors: Basu, Uttiya, Meng, Fei-Long, Keim, Celia, Grinstein, Veronika, Pefanis, Evangelos, Eccleston, Jennifer, Zhang, Tingting, Myers, Darienne, Wesemann, Duane R., Januszyk, Kurt, Gregory, Richard I., Deng, Haiteng, Lima, Christopher D., Alt, Frederick W.
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3065114/
https://ncbi.nlm.nih.gov/pubmed/21255825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.01.001
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