The RNA Exosome Targets the AID Cytidine Deaminase to Both Strands of Transcribed Duplex DNA Substrates

Activation Induced cytidine Deaminase (AID) initiates Immunoglobulin (Ig) heavy chain (IgH) class switch recombination (CSR) and Ig variable region somatic hypermutation (SHM) in B lymphocytes by deaminating cytidines on template and non-template strands of transcribed DNA substrates. However, the m...

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Detalhes bibliográficos
Main Authors: Basu, Uttiya, Meng, Fei-Long, Keim, Celia, Grinstein, Veronika, Pefanis, Evangelos, Eccleston, Jennifer, Zhang, Tingting, Myers, Darienne, Wesemann, Duane R., Januszyk, Kurt, Gregory, Richard I., Deng, Haiteng, Lima, Christopher D., Alt, Frederick W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3065114/
https://ncbi.nlm.nih.gov/pubmed/21255825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.01.001
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