Metabotropic glutamate mGlu2 receptor is necessary for the pharmacological and behavioral effects induced by hallucinogenic 5-HT2A receptor agonists

Hallucinogenic drugs, including mescaline, psilocybin and lysergic acid diethylamide (LSD), act at serotonin 5-HT2A receptors (5-HT2ARs). Metabotropic glutamate receptor 2/3 (mGluR2/3) ligands show efficacy in modulating the responses induced by activation of 5-HT2ARs. The formation of a 5-HT2AR-mGl...

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Autori principali: Moreno, José L., Holloway, Terrell, Albizu, Laura, Sealfon, Stuart C., González-Maeso, Javier
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064746/
https://ncbi.nlm.nih.gov/pubmed/21276828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2011.01.046
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