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HDAC Inhibition Decreases the Expression of EGFR in Colorectal Cancer Cells

Epidermal growth factor receptor (EGFR), a receptor tyrosine kinase which promotes cell proliferation and survival, is abnormally overexpressed in numerous tumors of epithelial origin, including colorectal cancer (CRC). EGFR monoclonal antibodies have been shown to increase the median survival and a...

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Hlavní autoři: Chou, Chia-Wei, Wu, Ming-Shiang, Huang, Wei-Chien, Chen, Ching-Chow
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064594/
https://ncbi.nlm.nih.gov/pubmed/21464950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018087
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