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HDAC Inhibition Decreases the Expression of EGFR in Colorectal Cancer Cells
Epidermal growth factor receptor (EGFR), a receptor tyrosine kinase which promotes cell proliferation and survival, is abnormally overexpressed in numerous tumors of epithelial origin, including colorectal cancer (CRC). EGFR monoclonal antibodies have been shown to increase the median survival and a...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3064594/ https://ncbi.nlm.nih.gov/pubmed/21464950 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018087 |
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