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A role for UDP-glucose glycoprotein glucosyltransferase in expression and quality control of MHC class I molecules
UDP-glucose:glycoprotein glucosyltransferase 1 (UGT1) serves as a folding sensor in the calnexin/calreticulin glycoprotein quality control cycle. UGT1 recognizes disordered or hydrophobic patches near asparagine-linked nonglucosylated glycans in partially misfolded glycoproteins and reglucosylates t...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3064381/ https://ncbi.nlm.nih.gov/pubmed/21383159 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1102527108 |
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