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Essential glycan-dependent interactions optimize MHC class I peptide loading

In this study we sought to better understand the role of the glycoprotein quality control machinery in the assembly of MHC class I molecules with high-affinity peptides. The lectin-like chaperone calreticulin (CRT) and the thiol oxidoreductase ERp57 participate in the final step of this process as p...

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Detalhes bibliográficos
Main Authors: Wearsch, Pamela A., Peaper, David R., Cresswell, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064348/
https://ncbi.nlm.nih.gov/pubmed/21383180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1102524108
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