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Molecular recognition and substrate mimicry drive the electron-transfer process between MIA40 and ALR

Oxidative protein folding in the mitochondrial intermembrane space requires the transfer of a disulfide bond from MIA40 to the substrate. During this process MIA40 is reduced and regenerated to a functional state through the interaction with the flavin-dependent sulfhydryl oxidase ALR. Here we prese...

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Main Authors: Banci, Lucia, Bertini, Ivano, Calderone, Vito, Cefaro, Chiara, Ciofi-Baffoni, Simone, Gallo, Angelo, Kallergi, Emmanouela, Lionaki, Eirini, Pozidis, Charalambos, Tokatlidis, Kostas
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064372/
https://ncbi.nlm.nih.gov/pubmed/21383138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1014542108
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