Prospective separation of normal and leukemic stem cells based on differential expression of TIM3, a human acute myeloid leukemia stem cell marker

Hematopoietic tissues in acute myeloid leukemia (AML) patients contain both leukemia stem cells (LSC) and residual normal hematopoietic stem cells (HSC). The ability to prospectively separate residual HSC from LSC would enable important scientific and clinical investigation including the possibility...

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Bibliographic Details
Main Authors: Jan, Max, Chao, Mark P., Cha, Adriel C., Alizadeh, Ash A., Gentles, Andrew J., Weissman, Irving L., Majeti, Ravindra
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2011
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064328/
https://ncbi.nlm.nih.gov/pubmed/21383193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1100551108
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