Prospective separation of normal and leukemic stem cells based on differential expression of TIM3, a human acute myeloid leukemia stem cell marker

Hematopoietic tissues in acute myeloid leukemia (AML) patients contain both leukemia stem cells (LSC) and residual normal hematopoietic stem cells (HSC). The ability to prospectively separate residual HSC from LSC would enable important scientific and clinical investigation including the possibility...

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Bibliografski detalji
Glavni autori: Jan, Max, Chao, Mark P., Cha, Adriel C., Alizadeh, Ash A., Gentles, Andrew J., Weissman, Irving L., Majeti, Ravindra
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2011
Teme:
Biological Sciences
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064328/
https://ncbi.nlm.nih.gov/pubmed/21383193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1100551108
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