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TAK1 signaling maintains intestinal integrity by preventing accumulation of reactive oxygen species in the intestinal epithelium

The intestinal epithelium is constantly exposed to inducers of reactive oxygen species (ROS) such as commensal microorganisms. Levels of ROS are normally maintained at non-toxic levels, but dysregulation of ROS is involved in intestinal inflammatory diseases. Here we report that TGFβ-activated kinas...

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書誌詳細
主要な著者: Kajino-Sakamoto, Rie, Omori, Emily, Nighot, Prashant K., Blikslager, Anthony T., Matsumoto, Kunihiro, Ninomiya-Tsuji, Jun
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064262/
https://ncbi.nlm.nih.gov/pubmed/20855879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903587
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