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TAK1 signaling maintains intestinal integrity by preventing accumulation of reactive oxygen species in the intestinal epithelium

The intestinal epithelium is constantly exposed to inducers of reactive oxygen species (ROS) such as commensal microorganisms. Levels of ROS are normally maintained at non-toxic levels, but dysregulation of ROS is involved in intestinal inflammatory diseases. Here we report that TGFβ-activated kinas...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Kajino-Sakamoto, Rie, Omori, Emily, Nighot, Prashant K., Blikslager, Anthony T., Matsumoto, Kunihiro, Ninomiya-Tsuji, Jun
פורמט: Artigo
שפה:Inglês
יצא לאור: 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064262/
https://ncbi.nlm.nih.gov/pubmed/20855879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903587
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