Elevated miR-155 Promotes Inflammation in Cystic Fibrosis by Driving Hyperexpression of Interleukin-8

Cystic Fibrosis (CF) is characterized by a massive proinflammatory phenotype in the lung arising from profound expression of inflammatory genes, including interleukin-8 (IL-8). We have previously reported that IL-8 mRNA is stabilized in CF lung epithelial cells, resulting in concomitant hyperexpress...

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Detalhes bibliográficos
Main Authors: Bhattacharyya, Sharmistha, Balakathiresan, Nagaraja S., Dalgard, Clifton, Gutti, Usha, Armistead, David, Jozwik, Cathy, Srivastava, Meera, Pollard, Harvey B., Biswas, Roopa
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064214/
https://ncbi.nlm.nih.gov/pubmed/21282106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.198390
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