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Digitoxin induces apoptosis in cancer cells by inhibiting nuclear factor of activated T-cells-driven c-MYC expression

BACKGROUND: Cardiac glycosides such as digitoxin have been shown to directly cause apoptotic death of cancer cells both in vitro, and in vivo. However, the mechanism connecting cardiac glycoside action to apoptosis is not known. It has been reported that compounds resembling digitoxin are able to re...

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Bibliografski detalji
Glavni autori: Yang, Qing Feng, Dalgard, Clifton L., Eidelman, Ofer, Jozwik, Catherine, Pollard, Bette S., Srivastava, Meera, Pollard, Harvey B.
Format: Artigo
Jezik:Inglês
Izdano: Medknow Publications & Media Pvt Ltd 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3709410/
https://ncbi.nlm.nih.gov/pubmed/23858296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1477-3163.112268
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