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Tristetraprolin regulates IL-8 mRNA stability in cystic fibrosis lung epithelial cells
Cystic fibrosis (CF) is due to mutations in the CFTR gene and is characterized by hypersecretion of the proinflammatory chemokine IL-8 into the airway lumen. Consequently, this induces the highly inflammatory cellular phenotype typical of CF. Our initial studies revealed that IL-8 mRNA is relatively...
Tallennettuna:
| Päätekijät: | , , , , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Physiological Society
2009
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2692809/ https://ncbi.nlm.nih.gov/pubmed/19363120 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.90601.2008 |
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