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Pharmacogenomics of the cystic fibrosis transmembrane conductance regulator (CFTR) and the cystic fibrosis drug CPX using genome microarray analysis.

BACKGROUND: Cystic fibrosis (CF) is the most common lethal recessive disease affecting children in the U.S. and Europe. For this reason, a number of ongoing attempts are being made to treat the disease either by gene therapy or pharmacotherapy. Several phase 1 gene therapy trials have been completed...

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Main Authors: Srivastava, M., Eidelman, O., Pollard, H. B.
Format: Artigo
Sprog:Inglês
Udgivet: The Feinstein Institute for Medical Research 1999
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2230479/
https://ncbi.nlm.nih.gov/pubmed/10656877
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